Variants of Kannan's Theorem are given where the circuits of the original theorem are replaced by arbitrary recursively presentable classes of languages that use advice strings and satisfy certain mild conditions. These variants imply that $\DTIME(n^{k'})^{\NE}/n^k$ does not contain $\PTIME^{\NE}$, $\DTIME(2^{n^{k'}})/n^k$ does not contain $\EXP$, $\SPACE(n^{k'})/n^k$ does not contain $\PSPACE$, ...
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