In sequencing by hybridization (SBH), one has to reconstruct a sequence from its $l$-long substrings. SBH was proposed as an alternative to gel-based DNA sequencing approaches, but in its original form the method is not competitive. Positional SBH (PSBH) is a recently proposed enhancement of SBH in which one has ... more >>>

The breakpoint distance between two $n$-permutations is the number of pairs that appear consecutively in one but not in the other. In the median problem for breakpoints one is given a set of permutations and has to construct a permutation that minimizes the sum of breakpoint distances to all the ... more >>>